Avocado - Further Health Benefits

Healthy heart food avocado

Supports Cardiovascular Health

Avocado’s support for heart and blood vessels might be surprising to some people who think about avocado as too high in fat for heart health. From a research standpoint, however, many metabolic aspects of heart health - including levels of inflammatory risk factors, levels of oxidative risk factors, and blood fat levels (including level of total cholesterol) - are improved by avocado. In addition, we know that heart health is improved by intake of oleic acid (the primary fatty acid in avocado) and by intake of omega-3 fatty acids (provided by avocado in the form of alpha-linolenic acid and in the amount of 160 milligrams per cup). Since elevated levels of homocysteine form a key risk factor for heart disease, and since B vitamins are very important for healthy regulation of homocysteine levels, avocado’s significant amounts of vitamin B-6 and folic acid provide another channel of heartsupport.

Research on avocado and heart disease remains in the preliminary stage, with studies mostly limited to lab studies on cells or animals fed avocado extracts. But we fully expect to see large-scale human studies confirming the heart health benefits of this unique food.

The monounsaturated fats in avocados

Promotes Blood Sugar Regulation

One of the most fascinating areas of avocado research—and one that may turn out to be the most unique for health support—involves carbohydrates and blood sugar regulation. Avocado is relatively low-carb food, with about 19% of its calories coming from carbs. It’s also a low-sugar food, containing less than 2 grams of total sugar per cup, and falls very low on the glycemic index. At the same time, one cup of avocado provides about 7-8 grams of dietary fiber, making it an important dietary source of this blood sugar-regulating nutrient. Given this overall carb profile, we would not expect avocado to be a problematic food for blood sugar unless it was eaten in excessive amounts (many cups per serving).

Within its relatively small carb content, however, avocado boasts some of the most unusual carb components in any food. When it is still on the tree, avocado contains about 60% of its carbs in the form of 7-carbon sugars. In sizable amounts, 7-carbon sugars (like mannoheptulose, the primary carb in unripened avocado) are rarely seen in foods. Because of their rare status, food scientists have been especially interested in the 7-carbon sugars (mannoheptulose, sedoheptulose, and related sugar alcohols like perseitol) found in avocado. The 7-carbon sugars like mannoheptulase may help regulate the way that blood sugar (glucose) is metabolized by blocking activity of an enzyme called hexokinase and changing the level of activity through a metabolic pathway called glycolysis. Research in this area is still a long way from determining potential health benefits for humans from dietary intake of these 7-carbon sugars. But it’s an exciting area of potential health benefit for avocado, especially since this food is already recognized as low glycemic index.

One final interesting observation comes from this research on avocado and its carbs: after five days of ripening (postharvest, beginning with removal of the avocado from the tree), the carb profile of avocado changes significantly. The 7-carbon sugars change from being the predominant form of carbs in avocado (60%) to being an important but minority component (between 40-50% of total carbs). With ripening, the 5-carbon sugars—especially sucrose —become the predominant carbs. While it’s too early in the research process to draw health-oriented conclusions from this information, these findings may be encouraging us to consider degree of avocado ripeness as an important factor in its health benefits. We already know to stay away from an extremely overripe avocado that has become overly soft and has developed dark sunken spots on its skin. Perhaps off in the future, we’ll be able to zero in on exact amounts of avocado ripeness that offers different types of unique health benefits, including carb-related benefits.

Avocado has many potential benefits in health care

Anti-Cancer Benefits

The ability of avocado to help prevent the occurrence of cancers in the mouth, skin, and prostate gland has been studied in a preliminary way by health researchers, mostly through the use of lab studies on cancer cells or lab studies involving animals and their consumption of avocado extracts. But even though this anti-cancer research has been limited with respect to humans and diet, we believe that the preliminary results are impressive.

The anti-cancer properties of avocado are definitely related to its unusual mix of anti-inflammatory and antioxidant nutrients. That relationship is to be expected since cancer risk factors almost always include excessive inflammation (related to lack of anti-inflammatory nutrients) and oxidative stress (related to lack of antioxidants).

But here is where the avocado story gets especially interesting. In healthy cells, avocado works to improve inflammatory and oxidative stress levels. But in cancer cells, avocado works to increase oxidative stress and shift the cancer cells over into a programmed cell death cycle (apoptosis), lessening the cancer cell numbers. In other words, avocado appears to selectively push cancer cells “over the brink” in terms of oxidative stress and increase their likelihood of dying, while at the same time actively supporting the health of non-cancerous cells by increasing their supply antioxidant and anti-inflammatory nutrients. We look forward to large-scale studies in this area involving humans and dietary consumption of avocado.